PATENTS(issued and applied for)

  • Synthetic sphingolipid drugs active against solid tumors, A. Edinger, S. Hanessian PCT, filed 06/14/2018
  • A. Edinger, S. Hanessian, Compounds and Methods for Increased Antisense Activity, U.S. provisional application serial no. 62/675,536, filed on May 23, 2018.
  • A. Edinger, S. Hanessian, Synthetic Sphingolipid-Like Molecules, Drugs, Methods of Their Synthesis and Methods of Treatment, US Patent Application PCT US2016053815, filed on March 14, 2018
  • A. Edinger, S. Hanessian, Azacyclic constrained analogs of FTY720, US. Patent No- 10,077,236 B2 Sept 18 2018
  • P.P. Seth, E.E. Swayze, S. Hanessian, B. R. Schroeder, R. D. Giacometti, B.L. Merner, Tricyclic Nucleic Acid Analogs, Int. Patent, WO2013154798/99, October 17, 2013.
  • P. P. Seth, E. E. Swayze, S. Hanessian, B. R. Schroeder, Bicyclic nucleosides and oligomeric compounds prepared therefrom, Int. Patent, WO2011156278, December 15, 2011.
  • J.P. Maianti, J. B. Aggen, P. Dozzo, A. A. Goldblum, D. J. Hildebrandt, T. R. Kane, M. J. Gliedt, M. S. Linsell, S. Hanessian, A. Giguère, Antibacterial Aminoglycoside Analogs, Int. Patent, WO2011/044498, April 14, 2011.
  • S. Hanessian, D. K. Maji, Z. Shao, G. Subramaniyan, M. Tintelnot-Blomley, G. Yang, H. Yun, Substituted Cyclohexanecarboxamides useful as Bace Inhibitors, Int. patents, WO2009/013293, January 29, 2009.
  • E.Swazye, S. Hanessian, J. Szychowski, S. S. Adhikari, K. Pachamuthu, X. Wang, M. T. Migawa, R. H. Griffey, Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents, US Patent, Appl. 12/"130,048,  May 30, 2008.
  • S. Hanessian, K. Patchamuthu, E. Klegraf, A. Goldblum, M. Linsell, J. Aggen, H. Moser, Antibacterial 1,4,5-substituted aminoglycoside analogs, US patent.  Appl. No. 12/100,981, April 10, 2008.
  • E. E. Swayze, S. Hanessian, J. Szychowski, S. S. Adhikari, K. Pachamuthu, X. Wang, M. T. Migawa, R. H. Griffey, Preparation of antibacterial 4,5-substituted aminoglycoside analogs for use as prophylactic or therapeutics against  microbial infection WO 2007064954 (2007).
  • S. Hanessian, K. Jankowski, C. Hocquelet, Dérivés de cyclodextrines (filed August 9, 2007), Brevet français  07/05816.
  • S. Hanessian, G. Yang, H. Yun, G. Subramaniyan, D. K. Majir,  Z. Shao, C. Betschart, M. Tintelnot-Blomley, Cycloalkylcarboxamides as Inhibitors of Aspartyl Proteases, US pat. (filed March 20, 2007).
  • S. Hanessian, L. Auzzas, G. Giannin, C. Pisano, L. Vesci, Amide Compounds and their Use as Antitumor Agents, 539- EP (European Patent Application) (filed March 13, 2007).
  • S. Hanessian, J. Szychowski, S. S. Adhikari, K. Pachamuthu, M. T. Migawa, R. H. Griffey, E. E. Swayze,  Antimicrobial 2-deoxystreptamine compounds, WO2006/05930  (2006).
  • S. Hanessian, E. Therrien, W. van Otterlo, K. Berggren, O. Davidsson, O. Fjellstrom, D. Gustafsson, T. Inghardt, M. Nagard, I. Nilsson,  New 5,6-dihydropyridine-2-one compounds useful as inhibitors of thrombin, Swedish pat. WO 2005058826 (2005).
  • S. Hanessian, E. Therrien, M. Bayrakdarian, D. Simard, Preparation of pyridinones useful as thrombin inhibitors, Swedish pat. WO2005075424 (2005).
  • S. Hanessian, S. Marcotte, G. Huang, P. Crowley, P. Jelf, O. Loiseleur, Preparation of novel 2,7-dioxo-bicyclo[4.3.0]non-5-yl-urea derivatives as plant fungicides, British Patent WO2004069842 A1, (2004).
  • S. Hanessian, R. Machaalani, S. Marcotte, Process to prepare malayamycin derivatives as antifungal, British Patent WO2004069842 A1 (2004).
  • S. Hanessian, N. Moitessier, B. Mackay, J. Hickman, G. Tucker, D.-H. Caignard and P. Renard, Nouveaux dérivés d’acide hydroxamique, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent, Dépôt Initial France, 0100312, (filed November 1, 2001).
  • S. Hanessian, N. Moitessier, C. Gauchet, J. Hickman, G. Tucker, D.H. Caignard, and P.Renard, Nouveaux dériviés d’acide hydroxamique, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent, Dépôt Initial France 0100313, (filed November 1, 2001).
  • S. Hanessian, M. Bayrakdarian, X. Luo, et al. Inhibitors of Neuraminidases, PCT WO 01/28996 A2, April 26, 2001.
  • S. Hanessian, J. Wang, et al. 1-cyclohexene-1-carboxylic acid and 1-cyclohexene-1-carboxylates as Neuraminidase Inhibitors, PCT WO 01/28981 A1, April 26, 2001.
  • S. Hanessian, J. Wang, et al. Neuramidase Inhibitors, PCT WO 01/29021 A1, April 26, 2001.
  • S. Hanessian, A. Ghanem, G. Tucker, D.-H. Caignard and P. Renard, Nouveaux dérivés d’acide hydroxamique, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent, Dépôt Initial France, 99402016.2 (filed August 9, 1999).
  • S. Hanessian and M. Rozema, Isomerization Process, Eur. Pat. 871635 (1998).
  • S. Hanessian and M. Rozema, Isomerization process for obtaining 4(S)-Methoxycyclohexane Intermediate in Trinem Synthesis, PCT WO 97/06174 (1997).
  • S. Hanessian, Stereocontrolled Solution and Solid Phase Glycosidation, U.S. Patent 5,767,256 (1998).
  • S. Hanessian, Amino-cyclodextrin syntheses, U.S. Patent (filed Jan. 16, 1996).
  • S. Hanessian, Synthesis of Prototypes for Renin Inhibitors, PCT WO95/29150, International (filed April 12, 1995).
  • S. Hanessian, Amino-cyclodextrins and related structures, Can. Patent, (filed. July 19, 1993).
  • D. Archard, S. Grisoni, S. Hanessian, C. Moutonnier, J.F. Peyronel, M. Tabart et A. Truchon, Nouveaux dérivés de perhydroisoindole, leur préparation et les compositions pharmaceutiques qui les contiennent, Eur. Pat. 92401329.5 (1993).
  • D. Archard, S. Grisoni, S. Hanessian, C. Moutonnier, J.F. Peyronel, M. Tabart et A. Truchon, Nouveaux dérivés de perhydroisoindole, leur préparation, Eur. Pat. 92401330.3 (1993).
  • S. Hanessian and T. Theophanides, Hydroxy Substituted Platinum diamine compounds, Can. Patent,  1,282,058 (1991).
  • S. Hanessian and D. Dubé, Deconjugation and Epimerization Process for the Avermectins, Can. Patent, 1,282,061 (1991).
  • S. Hanessian, Cis-Platinum Derivatives, British Patent, 8,722,354 (1990).
  • S. Hanessian, Preparation of Aminoglycosides, Can. Patent 1,271,744  (1990).
  • S. Hanessian, O-Alkyl Platinum Diamine Compounds, Can. Patent , 1,265,811 (1990).
  • S. Hanessian and M. Kagotani, Process for Selectively Deacetylating Acetyl Derivatives of Saccharides, U.S. Patent, 4,765,605 (1988).
  • S. Hanessian, Interactive, Computerized Apparatus and Method for the Analysis and Perception of Stereochemical Features in Molecules, and for the Selection of precursors in Organic Synthesis, Can. Patent, serial 528,615, filed January 30, 1987.
  • S. Hanessian and M. Alpegiani, 6α- and β-(substituted methyl)-penicillannic acid derivatives, British Patent, 8,716,300 (1991).
  • S. Hanessian and A. Bedeschi, Process for the synthesis of penems and penams, U.S. Patent, 4,663,451 (1987).
  • A.M. Nadzan, A.G. Pernet, S. Hanessian, High Caloric Product for I.V. Administration, U.S. Patent 4,572,907 (1986).
  • S. Hanessian, Aminoglycoside Antibiotic Derivatives and Process for Their Production, U.S. Patent, 4,247,687 (1981).
  • S. Hanessian and R. Carney, 1-N-Substituted Derivatives of Seldomycin Factor 5, U.S. Patent, 4,2l4,077 (1980).
  • S. Hanessian, Neomycins and Paromomycin Derivatives, U.S. Patent  4,066,753 (1978).
  • T.H. Haskell and S. Hanessian, 9-(β -D-arabinofuranosyl)adenine Esters and Methods for their Production, U.S. Patent  3,65l,045 (1972).
  • S. Hanessian, 9-(β-D-arabinofuranosyl)-6(amidino)purine Compounds and Methods for their Production, U.S. Pat. 3,472,838 (1969); German Pat. 1,811,267 (1969); Can. Pat. 869,537 (1971).
  • S. Hanessian and G. Schutze, Synthetic Penicillins Derived from Cycloheptatriene Carboxylic Acids, U.S. Pat. 3,457,257 (1969).
  • M.W. Fisher and S. Hanessian, Polyvalent Pseudomonas Antigens, British Pat. 1,155,683 (1969); Can. Pat. 851,163 (1970); 878,461 (1971).
  • T.H. Haskell and S. Hanessian, Soluble Antigens from Bordetella Pertussis, U.S. Pat. 3,405,218 (1965); Can. Pat. 809,630 (1969).
 
 
 
 
 
 
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