CONTACT INFORMATION
(514) 343-6738
(514) 343-5728 (FAX)
stephen.hanessian@umontreal.ca
(514) 343-5728 (FAX)
stephen.hanessian@umontreal.ca
AFFILIATION
● Department of Chemistry, University of Montreal
● Ionis Pharmaceuticals Research Chair
● NSERC/ Servier Senior Industrial Research Chair
1960 PhD Ohio State University (with Prof. M. L. Wolfrom)
1961-1968 Parke Davis & Co., Ann Arbor, Michigan
1969-1970 University of Montreal, Associate Professor
1970-1979 University of Montreal, Professor
1979-2003 McConnell Professor of Chemistry
1973-present Invited visiting professorships: Paris, Rochester, MIT, Strasbourg, Lyon, Rome, Siena
1990-1995 NSERCC - Chair in Medicinal Chemistry
2000-2006 Adjunct Professor of Chemistry and Chemical Biology, University of California, Irvine
2003-present Ionis Pharmaceuticals Research Chair
2005-2012 Achaogen Research Chair
2006-present Distinguished Professor, Departments of Chemistry, Pharmaceutical Sciences, and Pharmacology at the University of California, Irvine
2006-present Director of the Medicinal Chemistry and Pharmacology (MCP) Graduate Program at the University of California, Irvine
2018-2023 NSERC/ Servier Senior Industrial Research Chair
● Ionis Pharmaceuticals Research Chair
● NSERC/ Servier Senior Industrial Research Chair
1960 PhD Ohio State University (with Prof. M. L. Wolfrom)
1961-1968 Parke Davis & Co., Ann Arbor, Michigan
1969-1970 University of Montreal, Associate Professor
1970-1979 University of Montreal, Professor
1979-2003 McConnell Professor of Chemistry
1973-present Invited visiting professorships: Paris, Rochester, MIT, Strasbourg, Lyon, Rome, Siena
1990-1995 NSERCC - Chair in Medicinal Chemistry
2000-2006 Adjunct Professor of Chemistry and Chemical Biology, University of California, Irvine
2003-present Ionis Pharmaceuticals Research Chair
2005-2012 Achaogen Research Chair
2006-present Distinguished Professor, Departments of Chemistry, Pharmaceutical Sciences, and Pharmacology at the University of California, Irvine
2006-present Director of the Medicinal Chemistry and Pharmacology (MCP) Graduate Program at the University of California, Irvine
2018-2023 NSERC/ Servier Senior Industrial Research Chair
AWARDS
1974 Merck Sharpe & Dohme Award (Chemical Institute of Canada)
1982 C.S. Hudson Award (American Chemical Society)
1987 Urgel-Archambault Award, Quebec Association for the Advancement of Science
1988 CIC Palladium Medal (Chemical Institute of Canada)
1988 Alfred Bader Award in Organic Chemistry (Canadian Society for Chemistry)
1988 Fellow, Royal Society of Canada
1989 Fellow, Killam Foundation
1990 NSERCC - Chair in Medicinal Chemistry
1991 Bell Canada-Forum Award
1992 E. Smissman Medal, University of Kansas
1993 M.L. Wolfrom Award (American Chemical Society)
1996 A.C. Cope Scholar Award (American Chemical Society)
1996 Canada Gold Medal for Science and Engineering
1996 Prix Marie-Victorin, Quebec Science Prize
1996 Science Personality of the Year (La Presse)
1997 Killam Memorial Prize (Natural Sciences)
1997 Compagnon Lavoisier (Quebec Order of Chemists)
1998 Officer of the Order of Canada
2001 Doctorate Honoris Causa, University of Siena, Italy
2001 Bernard Belleau Award in Medicinal Chemistry (CSC)
2001 Doctorate Honoris Causa, University of Moncton, NB, Canada
2002 Queen Elisabeth Golden Jubilee Medal
2003 Ionis Pharmaceuticals Research Chair
2006 Doctorate Honoris Causa, University of Urbino, Italy
2008 Ionis Pharmaceuticals Research Chair
2008 Elected Foreign Member, National Academy of Sciences, Republic of Armenia
2011 First FQRNT Quebec Science Prize
2012 Ernest Guenther Award in Natural Products, (American Chemical Society)
2012 IUPAC-Richter Prize in Medicinal Chemistry
2012 Montreal In Vivo Award
1982 C.S. Hudson Award (American Chemical Society)
1987 Urgel-Archambault Award, Quebec Association for the Advancement of Science
1988 CIC Palladium Medal (Chemical Institute of Canada)
1988 Alfred Bader Award in Organic Chemistry (Canadian Society for Chemistry)
1988 Fellow, Royal Society of Canada
1989 Fellow, Killam Foundation
1990 NSERCC - Chair in Medicinal Chemistry
1991 Bell Canada-Forum Award
1992 E. Smissman Medal, University of Kansas
1993 M.L. Wolfrom Award (American Chemical Society)
1996 A.C. Cope Scholar Award (American Chemical Society)
1996 Canada Gold Medal for Science and Engineering
1996 Prix Marie-Victorin, Quebec Science Prize
1996 Science Personality of the Year (La Presse)
1997 Killam Memorial Prize (Natural Sciences)
1997 Compagnon Lavoisier (Quebec Order of Chemists)
1998 Officer of the Order of Canada
2001 Doctorate Honoris Causa, University of Siena, Italy
2001 Bernard Belleau Award in Medicinal Chemistry (CSC)
2001 Doctorate Honoris Causa, University of Moncton, NB, Canada
2002 Queen Elisabeth Golden Jubilee Medal
2003 Ionis Pharmaceuticals Research Chair
2006 Doctorate Honoris Causa, University of Urbino, Italy
2008 Ionis Pharmaceuticals Research Chair
2008 Elected Foreign Member, National Academy of Sciences, Republic of Armenia
2011 First FQRNT Quebec Science Prize
2012 Ernest Guenther Award in Natural Products, (American Chemical Society)
2012 IUPAC-Richter Prize in Medicinal Chemistry
2012 Montreal In Vivo Award
RESEARCH INTERESTS
The design and synthesis of drug prototypes, total synthesis of medicinally important natural products, asymmetric synthesis, supramolecular assembly, peptidomimetics, glycomimetics, morphinomimetics, amino acids, carbohydrates, ligand design for catalysis and methodology, aspects of chemical biology and chemoproteomics.
Current projects:
Current projects:
- New methodologies in chemical proteomics to study the interaction of synthetic cytotoxic sphingolipids with target proteins.
- Ways to potentiate antisense oligonucleotide activity and delivery.
- Synthesis of constrained azacycles to probe CNS receptor interactions.
- Peptido- and glycomimetics to validate revelant enzyme active site interactions.
- Total synthesis and study of pharmacophoric elements of lignan, quinolone, and Daphniphyllum alkaloid bioactive natural products as anticancer, antiparasitic, antibiotic, and antifeedant agents.
- Reagent and catalyst design for asymmetric synthesis.
Consulting
Pharmaceutical, Biotech and Agrochemical Industries (Canada, USA, Europe)
Publications567
|
Patents51
|
Monographs
- Total Synthesis of Natural Products: The 'Chiron' Approach, Pergamon, 1983
- Preparative Carbohydrate Chemistry, Marcel Dekker Inc., 1997
- Design and Strategy in Organic Synthesis: From the Chiron Approach to Catalysis, VCH, August 2013 (794 pages)
- Natural Products in Medicinal Chemistry, 16 Chapters, S. Hanessian Editor. Wiley-VCH, March 2014 (630 pages)
- Preparative Carbohydrate Chemistry, Marcel Dekker Inc., 1997
- Design and Strategy in Organic Synthesis: From the Chiron Approach to Catalysis, VCH, August 2013 (794 pages)
- Natural Products in Medicinal Chemistry, 16 Chapters, S. Hanessian Editor. Wiley-VCH, March 2014 (630 pages)
PLENARY LECTURES
2019 ACS National Meeting Orlando,USA, Guenther Award speaker, April 1
Medicinal Chemistry Symposium, Chemical Institute of Canada Meeting, June 2
ACS National Meeting, San Diego, USA, Carbohydrate Division, August 25
2018 Symposium honoring M. Kuehne, University of Vermont, USA
French American Symposium, Orléans, France
Symposium honoring Victor Snieckus, Hamilton, Ontario, Canada,
2017 Medicinal Chemistry Symposium, University of California, Irvine, CA, USA
Gordon Research Conference Reactions and Processes, Stonehill College, MA, USA
2016 European Workshop on Drug Synthesis, Siena, Italy
Organic Chemistry Conference, Las Vegas, Nevada, USA
8th Central European Conference ‘Chemistry towards Biology’, Brno, Czech Republic
Pharmaceutical Chemistry Conference, Frankfurt, Germany
World Chemistry Conference, Toronto, Canada
Ischia School of Advanced Organic Chemistry, Ischia, Italy
2015 First Sidney Hecht Endowed Lecture, University of Virginia, USA
European Medicinal Chemistry Conference, Athens, Greece
14th International Congress on Amino Acids, Peptides and Proteins, Vienna, Austria
250th ACS National Meeting, Boston, USA
Intl. Congress on the Chemistry of Antibiotics and other Bioactive Compounds, Galveston,
Texas
2014 2nd International Congress on Bacteriology and Infectious Diseases, Chicago, USA
LTOS conference, Brock University, Ontario, Canada
Ischia School of Advanced Organic Chemistry, Ischia, Italy
Canadian Society for Chemistry, Vancouver, Canada
European Workshop on Drug Synthesis, Siena, Italy
Florida Heterocyclic and Synthetic Conference, Gainesville, Fl., USA
2013 Canadian Institute of Chemistry National meeting (CIC), Quebec City
ArmChemfront Conference, Yerevan, Armenia
2012 ACS Guenther Award Symposium, San Diego, USA
European Workshop in Drug Synthesis, Siena, Italy
ICPC Conference on Organophosphorus Chemistry, Rotterdam, Netherlands
Ischia School of Advanced Organic Chemistry, Ischia, Italy
European Conference in Medicinal Chemistry, Berlin Germany
2011 Congrès de l'ACFAS, Université de Sherbrooke, QC, Canada
Keynote Lecture CIC Meeting, Montreal, QC, Canada
Antibiotic Symposium, CIC Meeting, Montreal, QC, Canada
IIT Lecture, Genoa, Italy
1970-present: Over 500 invited and plenary lectures (academia and industries)
Editorial and Professional Activities
Member, Advisory Board Several Journals, Conferences, Biotech industry
Medicinal Chemistry Symposium, Chemical Institute of Canada Meeting, June 2
ACS National Meeting, San Diego, USA, Carbohydrate Division, August 25
2018 Symposium honoring M. Kuehne, University of Vermont, USA
French American Symposium, Orléans, France
Symposium honoring Victor Snieckus, Hamilton, Ontario, Canada,
2017 Medicinal Chemistry Symposium, University of California, Irvine, CA, USA
Gordon Research Conference Reactions and Processes, Stonehill College, MA, USA
2016 European Workshop on Drug Synthesis, Siena, Italy
Organic Chemistry Conference, Las Vegas, Nevada, USA
8th Central European Conference ‘Chemistry towards Biology’, Brno, Czech Republic
Pharmaceutical Chemistry Conference, Frankfurt, Germany
World Chemistry Conference, Toronto, Canada
Ischia School of Advanced Organic Chemistry, Ischia, Italy
2015 First Sidney Hecht Endowed Lecture, University of Virginia, USA
European Medicinal Chemistry Conference, Athens, Greece
14th International Congress on Amino Acids, Peptides and Proteins, Vienna, Austria
250th ACS National Meeting, Boston, USA
Intl. Congress on the Chemistry of Antibiotics and other Bioactive Compounds, Galveston,
Texas
2014 2nd International Congress on Bacteriology and Infectious Diseases, Chicago, USA
LTOS conference, Brock University, Ontario, Canada
Ischia School of Advanced Organic Chemistry, Ischia, Italy
Canadian Society for Chemistry, Vancouver, Canada
European Workshop on Drug Synthesis, Siena, Italy
Florida Heterocyclic and Synthetic Conference, Gainesville, Fl., USA
2013 Canadian Institute of Chemistry National meeting (CIC), Quebec City
ArmChemfront Conference, Yerevan, Armenia
2012 ACS Guenther Award Symposium, San Diego, USA
European Workshop in Drug Synthesis, Siena, Italy
ICPC Conference on Organophosphorus Chemistry, Rotterdam, Netherlands
Ischia School of Advanced Organic Chemistry, Ischia, Italy
European Conference in Medicinal Chemistry, Berlin Germany
2011 Congrès de l'ACFAS, Université de Sherbrooke, QC, Canada
Keynote Lecture CIC Meeting, Montreal, QC, Canada
Antibiotic Symposium, CIC Meeting, Montreal, QC, Canada
IIT Lecture, Genoa, Italy
1970-present: Over 500 invited and plenary lectures (academia and industries)
Editorial and Professional Activities
Member, Advisory Board Several Journals, Conferences, Biotech industry
